Package: RARtrials
Type: Package
Title: Response-Adaptive Randomization in Clinical Trials
Version: 0.0.1
Authors@R: c(person(given="Chuyao",
                    family="Xu",
                    role=c("aut","cre"),
                    email="cxu870@aucklanduni.ac.nz"),
            person(given="Thomas",
                    family="Lumley",
                    role=c("aut","ths"),
                    email="t.lumley@auckland.ac.nz"),
            person(given="Alain",
                    family="Vandal",
                    role=c("aut","ths"),
                    email="alain.vandal@auckland.ac.nz"),
            person(given="Sofia S.",
                    family="Villar",
                    role=c("cph"),
                    email="sofia.villar@mrc-bsu.cam.ac.uk"),
           person(given="Kyle J.",
                    family="Wathen",
                    role=c("cph"),
                    email="kylewathen@gmail.com")        
 )
Maintainer: Chuyao Xu <cxu870@aucklanduni.ac.nz>
Description: Some response-adaptive randomization methods commonly
        found in literature are included in this package. These methods
        include the randomized play-the-winner rule for binary endpoint
        (Wei and Durham (1978) <doi:10.2307/2286290>), the doubly
        adaptive biased coin design with minimal variance strategy for
        binary endpoint (Atkinson and Biswas (2013)
        <doi:10.1201/b16101>, Rosenberger and Lachin (2015)
        <doi:10.1002/9781118742112>) and maximal power strategy
        targeting Neyman allocation for binary endpoint (Tymofyeyev,
        Rosenberger, and Hu (2007) <doi:10.1198/016214506000000906>)
        and RSIHR allocation with each letter representing the first
        character of the names of the individuals who first proposed
        this rule (Youngsook and Hu (2010) <doi:10.1198/sbr.2009.0056>,
        Bello and Sabo (2016) <doi:10.1080/00949655.2015.1114116>),
        A-optimal Allocation for continuous endpoint (Sverdlov and
        Rosenberger (2013) <doi:10.1080/15598608.2013.783726>),
        Aa-optimal Allocation for continuous endpoint (Sverdlov and
        Rosenberger (2013) <doi:10.1080/15598608.2013.783726>),
        generalized RSIHR allocation for continuous endpoint (Atkinson
        and Biswas (2013) <doi:10.1201/b16101>), Bayesian
        response-adaptive randomization with a control group using the
        Thall \& Wathen method for binary and continuous endpoints
        (Thall and Wathen (2007) <doi:10.1016/j.ejca.2007.01.006>) and
        the forward-looking Gittins index rule for binary and
        continuous endpoints (Villar, Wason, and Bowden (2015)
        <doi:10.1111/biom.12337>, Williamson and Villar (2019)
        <doi:10.1111/biom.13119>).
Encoding: UTF-8
Collate: 'brar_select_au_binary.r' 'brar_select_au_known_var.r'
        'brar_select_au_unknown_var.r' 'convert_gamma_to_chisq.r'
        'convert_chisq_to_gamma.r' 'update_par_nichisq.r'
        'pgreater_beta.r' 'pgreater_normal.r' 'pgreater_NIX.r'
        'pmax_beta.r' 'pmax_normal.r' 'pmax_NIX.r' 'sim_brar_binary.r'
        'sim_brar_known_var.r' 'sim_brar_unknown_var.r'
        'flgi_cut_off_binary.r' 'flgi_cut_off_known_var.r'
        'flgi_cut_off_unknown_var.r' 'Gittins.r' 'sim_flgi_binary.r'
        'sim_flgi_known_var.r' 'sim_flgi_unknown_var.r'
        'dabcd_max_power.r' 'dabcd_min_var.r' 'sim_RPTW.r'
        'sim_A_optimal_known_var.r' 'sim_A_optimal_unknown_var.r'
        'sim_Aa_optimal_known_var.r' 'sim_Aa_optimal_unknown_var.r'
        'sim_dabcd_max_power.r' 'sim_dabcd_min_var.r'
        'sim_RSIHR_optimal_known_var.r'
        'sim_RSIHR_optimal_unknown_var.r' 'functions.r' 'RAR-package.r'
Depends: R(>= 4.3), stats, pins
Imports: Rdpack(>= 0.7)
RdMacros: Rdpack
RoxygenNote: 7.3.1
Suggests: knitr, rmarkdown, testthat (>= 3.0.0)
Config/testthat/edition: 3
VignetteBuilder: knitr
License: GPL (>= 3)
URL: https://github.com/yayayaoyaoyao/RARtrials
Config/pak/sysreqs: cmake make libuv1-dev libssl-dev
Repository: https://yayayaoyaoyao.r-universe.dev
Date/Publication: 2026-02-03 01:17:59 UTC
RemoteUrl: https://github.com/yayayaoyaoyao/rartrials
RemoteRef: HEAD
RemoteSha: 0aaf5bad2a97aefedd1d11453b4716c450c28a72
NeedsCompilation: no
Packaged: 2026-10-08 12:25:38 UTC; root
Author: Chuyao Xu [aut, cre],
  Thomas Lumley [aut, ths],
  Alain Vandal [aut, ths],
  Sofia S. Villar [cph],
  Kyle J. Wathen [cph]